Polyklonaler Anti-GET3-Antikörper von Solarbio

Name: Solarbio Anti-GET3 Polyclonal Antibody
SKU: 5835
Availability: InStock

$175.00 – $278.00

Versand USD 45 - Kostenlos über USD 300

DTE ist eine in China ansässige E-Commerce-Plattform, die sich auf den Online-Verkauf von molekularen Tests spezialisiert hat, ELISA, und verwandte Produkte.

Hersteller: Führende chinesische Marken
Versand: Beschleunigter FedEx-Versand direkt aus den Fabriken
Rückgabe oder Umtausch innerhalb von möglich 30 Tage
Zahlungsarten: Sicheres PayPal oder Kreditkarte.

Beschreibung

Attribut	Einzelheiten
Spezifikation	50ul / 100ul
Conjugation	Unconjugation
Host	Rabbit
Clonality	Polyclonal Antibody
Gene symbol	GET3
Immunogen	Recombinant protein of human GET3
Synonym	ASNA1; ARSA-I; ARSA1; ASNA-I; GET3; TRC40; hASNA-I
Isotype	IgG
Gene ID	439
Swiss Port	O43681
Molecular weight	39kDa
Purification	Affinity purification
Reactivity	Human, Mouse, Rat
Anwendung	IHC
Recommended dilution	IHC 1:50-200
Subcellular location	Cytoplasm, Kern
Lagerung	Store at -20°C. Avoid freeze/thaw cycles.
Hintergrund	ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Anschließend, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling.