Solarbio Anti-GET3 Polyclonal Antibody

Name: Solarbio Anti-GET3 Polyclonal Antibody
SKU: 5835
Availability: InStock

$175.00 – $278.00

Envío USD 45 - Gratis sobre USD 300

DTE es una plataforma de comercio electrónico con sede en China que se especializa en ventas en línea de pruebas moleculares., ELISA, y productos relacionados.

Fabricante: Marcas chinas líderes
Envío: Envío acelerado de FedEx directamente desde las fábricas
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Descripción

Atributo	Detalles
Especificación	50ul / 100ul
Conjugation	Unconjugation
Host	Rabbit
Clonality	Polyclonal Antibody
Gene symbol	GET3
Immunogen	Recombinant protein of human GET3
Synonym	ASNA1; ARSA-I; ARSA1; ASNA-I; GET3; TRC40; hASNA-I
Isotype	IgG
Gene ID	439
Swiss Port	O43681
Peso molecular	39kDa
Purification	Affinity purification
Reactivity	Human, Mouse, Rat
Solicitud	IHC
Recommended dilution	IHC 1:50-200
Subcellular location	Citoplasma, Núcleo
Almacenamiento	Conservar a -20°C. Avoid freeze/thaw cycles.
Background	ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling.