Solarbio Mouse Insulin Elisa Kit

Mouse Insulin Elisa Kit

Ne : SEKM-0141

Species :

Mouse
Assay Type :

Solid Phase Sandwich ELISA
Sensitivity :

0.09 ng/mL
Detection Range :

0.17-5.5 ng/mL
Assay Length :

3.5h
Sample Type :

Serum; Plasma; Cell culture supernatant; Urine; Tkivo.
Long Name :

Insulin
Synonyms :

IDDM; IDDM1; IDDM2; ILPR; INS; Insulin; IRDN; MODY10;
Background :

Insulin and the IGFs are members of the insulin family of molecules. IGF-I and II are structurally homologous to proinsulin, and can be thought of as taking the shape of an exaggerated, inverted letter G. Interchain disulfide bonds link sections of the G. The single chain insulin propeptide consists of a 30 amino acid B chain (aa 2554), a C-peptide (aa 5589), i a 21 aa A chain (aa 90110). Removal of the C-peptide by proteolysis enables the formation of mature Insulin, a disulfide linked heterodimer of the A and B chains. Circulating C-peptide levels are elevated in hyperinsulinism, obesity, and type II diabetes.