Solarbio Anti-GET3 Polyclonal Antibody

Name: Solarbio Anti-GET3 Polyclonal Antibody
SKU: 5835
Availability: InStock

$175.00 – $278.00

送料USD 45 - 米ドル以上は無料 300

DTE は、分子検査のオンライン販売に特化した中国に拠点を置く電子商取引プラットフォームです, エリサ, および関連製品.

属性	詳細
仕様	50ul / 100ul
Conjugation	Unconjugation
Host	Rabbit
Clonality	Polyclonal Antibody
Gene symbol	GET3
Immunogen	Recombinant protein of human GET3
Synonym	ASNA1; ARSA-I; ARSA1; ASNA-I; GET3; TRC40; hASNA-I
Isotype	IgG
Gene ID	439
Swiss Port	O43681
Molecular weight	39kDa
Purification	Affinity purification
Reactivity	Human, Mouse, Rat
応用	IHC
Recommended dilution	IHC 1:50-200
Subcellular location	Cytoplasm, 核
ストレージ	-20℃で保存. Avoid freeze/thaw cycles.
Background	ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling.