Mouse Insulin Elisa Kit
いいえ : SEKM-0141
Species :
Mouse
Assay Type :
Solid Phase Sandwich ELISA
Sensitivity :
0.09 ng/mL
Detection Range :
0.17-5.5 ng/mL
Assay Length :
3.5h
Sample Type :
血清; プラズマ; Cell culture supernatant; Urine; 組織.
Long Name :
Insulin
Synonyms :
IDDM; IDDM1; IDDM2; ILPR; INS; Insulin; IRDN; MODY10;
Background :
Insulin and the IGFs are members of the insulin family of molecules. IGF-I and II are structurally homologous to proinsulin, and can be thought of as taking the shape of an exaggerated, inverted letter G. Interchain disulfide bonds link sections of the G. The single chain insulin propeptide consists of a 30 amino acid B chain (aa 2554), a C-peptide (aa 5589), そして 21 aa A chain (aa 90110). Removal of the C-peptide by proteolysis enables the formation of mature Insulin, a disulfide linked heterodimer of the A and B chains. Circulating C-peptide levels are elevated in hyperinsulinism, obesity, and type II diabetes.
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