Solarbio 인간 에리스로포이에틴 (EPO) 엘리사 키트

인간 에리스로포이에틴 (EPO) 엘리사 키트

아니요 : 세크-0161

종 :

Human
분석 유형 :

고체상 샌드위치 ELISA
감광도 :

1.5 mIU/mL
감지 범위 :

3.1-200 mIU/mL
분석 길이 :

3.5시간
샘플 유형 :

혈청; 혈장; 세포 배양 상청액.
긴 이름 :

Erythropoietin
동의어 :

ECYT5; EP; EPO; epoetin; Erythropoietin; MGC138142; MVCD2
배경 :

Erythropoietin (EPO) is a 30-kDa, heavily glycosylated protein produced primarily by the kidney. It is the principal factor that regulates erythropoiesis. The production of EPO by kidney cells is increased in response to hypoxia or anemia. The cDNAs for EPO have been cloned from many species. The mature proteins from the various species are highly conserved, exhibiting greater than 80% sequence identity at the amino acid level.
The biological effects of EPO are mediated by the Erythropoietin receptor (EPO R). At the protein sequence level, the human EPO R is approximately 83% identical to the mouse protein. As a result of alternative splicing of the EPO R gene, cDNA clones encoding truncated soluble forms of EPO R have been found. Recombinant soluble EPO R binds EPO with high affinity and is a potent EPO antagonist.