Rat IL-10 Elisa Kit
아니요 : SEKR-0006
종 :
Rat
분석 유형 :
고체상 샌드위치 ELISA
감광도 :
15 pg/ml
감지 범위 :
15.6-1,000 pg/ml
분석 길이 :
3.5시간
샘플 유형 :
혈청; 혈장; 세포 배양 상청액.
긴 이름 :
Interleukin 10
동의어 :
IL10; CSIF; GVHDS; IL-10; IL10A; TGIF; Interleukin 10
배경 :
Interleukin-10 functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microenvironment, 하지만, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects, including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.
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