Anti-APOOL Polyclonal Antibody

Cat: K107649P

Summary:

【Product name】: Anti-APOOL antibody 【Source】: Rabbit

【Isotype】: IgG 【Species reactivity】: Human Mouse Rat

【Swiss Prot】: Q6UXV4 【Gene ID】: 139322

【Calculated】: MW:29kDa 【Observed】: MW:29kDa

【Purification】: Affinity purification

【Tested applications】: WB IHC

【Recommended dilution】: WB 1:1000-1:3000. IHC 1:50-200.

【WB Positive sample】: K-562,U937

【IHC Positive sample】: Human colorectal cancer

【Subcellular location】: Cytoplasm Cell membrane

【Immunogen】: A synthetic peptide of human APOOL

【Storage】: Shipped at 4 °C. Upon delivery, aliquot and store at -20 °C

Background:

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function.

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