Solarbio Anti-GET3 Polyclonal Antibody

Name: Solarbio Anti-GET3 Polyclonal Antibody
SKU: 5835
Availability: InStock

$175.00 – $278.00

Доставка в долларах США 45 - Бесплатно свыше долларов США 300

Размер

DTE — китайская платформа электронной коммерции, специализирующаяся на онлайн-продажах молекулярных тестов., ИФА, и сопутствующие товары.

Атрибут	Подробности
Спецификация	50ул / 100ул
Conjugation	Unconjugation
Host	Rabbit
Clonality	Polyclonal Antibody
Gene symbol	GET3
Immunogen	Recombinant protein of human GET3
Синоним	ASNA1; ARSA-I; ARSA1; ASNA-I; GET3; TRC40; hASNA-I
Isotype	IgG
Gene ID	439
Swiss Port	O43681
Молекулярная масса	39кДа
Очистка	Affinity purification
Reactivity	Human, Mouse, Rat
Приложение	IHC
Recommended dilution	IHC 1:50-200
Subcellular location	Цитоплазма, Ядро
Хранилище	Store at -20°C. Avoid freeze/thaw cycles.
Фон	ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Впоследствии, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling.