Solarbio抗GET3多株抗體

$175.00$278.00

運費美元 45 - 超過美元免費 300

DTE是一家專門從事分子檢測線上銷售的中國電子商務平台, 酵素連結免疫吸附試驗, 及相關產品.

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描述

屬性細節
規格50烏爾 / 100烏爾
ConjugationUnconjugation
Host兔子
ClonalityPolyclonal Antibody
Gene symbolGET3
免疫原Recombinant protein of human GET3
代名詞ASNA1; ARSA-I; ARSA1; ASNA-I; GET3; TRC40; hASNA-I
同型免疫球蛋白G
基因ID439
Swiss PortO43681
分子量39kDa
純化親和純化
Reactivity人類, 老鼠, Rat
應用免疫組化
推薦稀釋度免疫組化 1:50-200
亞細胞定位細胞質, 核
貯存儲存於-20°C. Avoid freeze/thaw cycles.
背景ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling.

附加資訊

尺寸

50烏爾, 100烏爾

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