屬性 | 細節 |
---|---|
規格 | 50烏爾 / 100烏爾 |
Conjugation | Unconjugation |
Host | 兔子 |
Clonality | Polyclonal Antibody |
Gene symbol | GET3 |
免疫原 | Recombinant protein of human GET3 |
代名詞 | ASNA1; ARSA-I; ARSA1; ASNA-I; GET3; TRC40; hASNA-I |
同型 | 免疫球蛋白G |
基因ID | 439 |
Swiss Port | O43681 |
分子量 | 39kDa |
純化 | 親和純化 |
Reactivity | 人類, 老鼠, Rat |
應用 | 免疫組化 |
推薦稀釋度 | 免疫組化 1:50-200 |
亞細胞定位 | 細胞質, 核 |
貯存 | 儲存於-20°C. Avoid freeze/thaw cycles. |
背景 | ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling. |
Solarbio抗GET3多株抗體
$175.00 – $278.00
運費美元 45 - 超過美元免費 300DTE是一家專門從事分子檢測線上銷售的中國電子商務平台, 酵素連結免疫吸附試驗, 及相關產品.
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描述
附加資訊
尺寸 | 50烏爾, 100烏爾 |
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